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Hyaluronan supports the limbal stem cell phenotype during ex vivo culture

BACKGROUND: Hyaluronan (HA) has previously been identified as an integral component of the limbal stem cell niche in vivo. In this study, we investigated whether a similar HA matrix is also expressed in vitro providing a niche supporting limbal epithelial stem cells (LESCs) during ex vivo expansion....

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Detalles Bibliográficos
Autores principales: Puri, Sudan, Moreno, Isabel Y., Sun, Mingxia, Verma, Sudhir, Lin, Xiao, Gesteira, Tarsis F., Coulson-Thomas, Vivien J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338506/
https://www.ncbi.nlm.nih.gov/pubmed/35907870
http://dx.doi.org/10.1186/s13287-022-03084-8