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Hyaluronan supports the limbal stem cell phenotype during ex vivo culture
BACKGROUND: Hyaluronan (HA) has previously been identified as an integral component of the limbal stem cell niche in vivo. In this study, we investigated whether a similar HA matrix is also expressed in vitro providing a niche supporting limbal epithelial stem cells (LESCs) during ex vivo expansion....
Autores principales: | Puri, Sudan, Moreno, Isabel Y., Sun, Mingxia, Verma, Sudhir, Lin, Xiao, Gesteira, Tarsis F., Coulson-Thomas, Vivien J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338506/ https://www.ncbi.nlm.nih.gov/pubmed/35907870 http://dx.doi.org/10.1186/s13287-022-03084-8 |
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