Bone morphogenetic protein 4 rescues the bone regenerative potential of old muscle-derived stem cells via regulation of cell cycle inhibitors

BACKGROUND: Bone morphogenetic protein 4 (BMP4) promotes the osteogenic differentiation and the bone regenerative potential of muscle-derived stem cells (MDSCs). BMP4 also promotes the self-renewal of both embryonic and somatic stem cells; however, BMP4 signaling activity significantly decreases wit...

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Detalles Bibliográficos
Autores principales: Cheng, Haizi, Gao, Xueqin, Huard, Matthieu, Lu, Aiping, Ruzbarsky, Joseph J., Amra, Sara, Wang, Bing, Huard, Johnny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338549/
https://www.ncbi.nlm.nih.gov/pubmed/35907860
http://dx.doi.org/10.1186/s13287-022-03047-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338549/
https://www.ncbi.nlm.nih.gov/pubmed/35907860
http://dx.doi.org/10.1186/s13287-022-03047-z

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