Cargando…

Bone morphogenetic protein 4 rescues the bone regenerative potential of old muscle-derived stem cells via regulation of cell cycle inhibitors

BACKGROUND: Bone morphogenetic protein 4 (BMP4) promotes the osteogenic differentiation and the bone regenerative potential of muscle-derived stem cells (MDSCs). BMP4 also promotes the self-renewal of both embryonic and somatic stem cells; however, BMP4 signaling activity significantly decreases wit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Haizi, Gao, Xueqin, Huard, Matthieu, Lu, Aiping, Ruzbarsky, Joseph J., Amra, Sara, Wang, Bing, Huard, Johnny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338549/ https://www.ncbi.nlm.nih.gov/pubmed/35907860 http://dx.doi.org/10.1186/s13287-022-03047-z

Ejemplares similares

Comparison of Autologous Blood Clots with Fibrin Sealant as Scaffolds for Promoting Human Muscle-Derived Stem Cell-Mediated Bone Regeneration
por: Gao, Xueqin, et al.
Publicado: (2021)

MRL/MpJ Mice Resist to Age-Related and Long-Term Ovariectomy-Induced Bone Loss: Implications for Bone Regeneration and Repair
por: Gao, Xueqin, et al.
Publicado: (2023)

Influences of donor and host age on human muscle-derived stem cell-mediated bone regeneration
por: Gao, Xueqin, et al.
Publicado: (2018)

Poster 107: The Use of Coacervate Sustained Release System to Identify the Most Potent BMP for Bone Regeneration
por: Huard, Johnny, et al.
Publicado: (2022)

A comparison of BMP2 delivery by coacervate and gene therapy for promoting human muscle-derived stem cell-mediated articular cartilage repair
por: Gao, Xueqin, et al.
Publicado: (2019)

Poster 247: Muscle ERRγ Overexpression Mitigates the Muscle Atrophy after ACL injury
por: Huard, Johnny, et al.
Publicado: (2022)

Effects of oral losartan administration on homeostasis of articular cartilage and bone in a rabbit model
por: Deng, Zhenhan, et al.
Publicado: (2022)

Improved Bone Quality and Bone Healing of Dystrophic Mice by Parabiosis
por: Li, Hongshuai, et al.
Publicado: (2021)

Two-stage therapeutic utility of ectopically formed bone tissue in skeletal muscle induced by adeno-associated virus containing bone morphogenetic protein-4 gene
por: Tian, Ke, et al.
Publicado: (2015)

Sustained Release of Bone Morphogenetic Protein 2 via Coacervate improves Muscle Derived Stem Cell Mediated Cartilage Regeneration in MIA-induced Osteoarthritis
por: Hicks, Justin James, et al.
Publicado: (2016)

Poster 206: TIPE2 Mitigates the Histopathology of Osteoarthritis in An Accelerate Aging Mouse Model
por: Huard, Matthieu, et al.
Publicado: (2022)

The superior regenerative potential of muscle-derived stem cells for articular cartilage repair is attributed to high cell survival and chondrogenic potential
por: Li, Hongshuai, et al.
Publicado: (2016)

Paper 40: Improved Cartilage Healing with Microfracture Augmented with Fisetin & Bone Marrow Aspirate Concentrate in Acute Osteochondral Defect
por: Gao, Xueqin, et al.
Publicado: (2022)

Partial Ablation of Non-Myogenic Progenitor Cells as a Therapeutic Approach to Duchenne Muscular Dystrophy
por: Gao, Zhanguo, et al.
Publicado: (2021)

Specific reprogramming of alpha cells to insulin-producing cells by short glucagon promoter-driven Pdx1 and MafA
por: Guo, Ping, et al.
Publicado: (2023)

Brown Fat Determination and Development from Muscle Precursor Cells by Novel Action of Bone Morphogenetic Protein 6
por: Sharma, Ankur, et al.
Publicado: (2014)

Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies
por: Stokovic, Nikola, et al.
Publicado: (2021)

Muscle-derived stem/progenitor cell dysfunction in Zmpste24-deficient progeroid mice limits muscle regeneration
por: Song, Minjung, et al.
Publicado: (2013)

Regenerative Translation of Human Blood-Vessel-Derived MSC Precursors
por: Chen, William C. W., et al.
Publicado: (2015)

Clonal Isolation of Muscle-Derived Cells Capable of Enhancing Muscle Regeneration and Bone Healing
por: Lee, Joon Yung, et al.
Publicado: (2000)

Bone regenerative effect of recombinant human bone morphogenetic protein-2 after cyst enucleation
por: Hwang, Doo Yeon, et al.
Publicado: (2016)

Cellular expansion of MSCs: Shifting the regenerative potential
por: Miclau, Katherine, et al.
Publicado: (2022)

In Vitro Evaluation of Recombinant Bone Morphogenetic Protein-2 Bioactivity for Regenerative Medicine
por: Fung, Stephanie L., et al.
Publicado: (2019)

Rapamycin Rescues Age-Related Changes in Muscle-Derived Stem/Progenitor Cells from Progeroid Mice
por: Kawakami, Yohei, et al.
Publicado: (2019)

Abstract QS18: Adipose Derived Stem Cells Isolated from Premature Aging Mice Show Sustained Stemness: Implications for Regenerative Medicine
por: Ravuri, Sudheer K., et al.
Publicado: (2018)

Effects of Fisetin Treatment on Cellular Senescence of Various Tissues and Organs of Old Sheep
por: Huard, Charles A., et al.
Publicado: (2023)

Reduction of senescent fibro‐adipogenic progenitors in progeria‐aged muscle by senolytics rescues the function of muscle stem cells
por: Liu, Lei, et al.
Publicado: (2022)

The role of the aging microenvironment on the fate of PDGFRβ lineage cells in skeletal muscle repair
por: Lu, Aiping, et al.
Publicado: (2022)

Expression and regulation of bone morphogenetic protein antagonists in vascular smooth muscle cells
por: Maciel, TT, et al.
Publicado: (2003)

Study of Muscle Cell Dedifferentiation after Skeletal Muscle Injury of Mice with a Cre-Lox System
por: Mu, Xiaodong, et al.
Publicado: (2011)

Bone Morphogenetic Proteins Shape T(reg) Cells
por: Kraj, Piotr
Publicado: (2022)

Terminal differentiation is not a major determinant for the success of stem cell therapy - cross-talk between muscle-derived stem cells and host cells
por: Gharaibeh, Burhan, et al.
Publicado: (2011)

Improvement of Cartilage Repair With Biologically Regulated Marrow Stimulation by Blocking TGF-β1 in A Rabbit Osteochondral Defect Model
por: Utsunomiya, Hajime, et al.
Publicado: (2019)

The beneficial effect of intra-articular injection of losartan on the microfracture mediated cartilage repair is dose dependent
por: Gao, Xueqin, et al.
Publicado: (2021)

Heterogenetic parabiosis between healthy and dystrophic mice improve the histopathology in muscular dystrophy
por: Lu, Aiping, et al.
Publicado: (2020)

The Classic: Bone Morphogenetic Protein
por: Urist, Marshall R., et al.
Publicado: (2009)

Bone morphogenetic protein-4 and bone morphogenetic protein receptors expressions in the adult rat eye
por: Maruyama-Koide, Yuka, et al.
Publicado: (2017)

The WNT Inhibitor Dickkopf 1 and Bone Morphogenetic Protein 4 Rescue Adipogenesis in Hypertrophic Obesity in Humans
por: Gustafson, Birgit, et al.
Publicado: (2012)

Bone Morphogenetic Protein-2 in Development and Bone Homeostasis
por: Halloran, Daniel, et al.
Publicado: (2020)

Rejuvenated Stem/Progenitor Cells for Cartilage Repair Using the Pluripotent Stem Cell Technology
por: Nakayama, Naoki, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pip1iehtoe22cgrlohpo3ale3q