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Fn14 exacerbates acute lung injury by activating the NLRP3 inflammasome in mice

BACKGROUND: Uncontrolled inflammation is an important factor in the occurrence and development of acute lung injury (ALI). Fibroblast growth factor-inducible 14 (Fn14), a plasma membrane-anchored receptor, takes part in the pathological process of a variety of acute and chronic inflammatory diseases...

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Detalles Bibliográficos
Autores principales: Guan, Xin-Xin, Yang, Hui-Hui, Zhong, Wen-Jing, Duan, Jia-Xi, Zhang, Chen-Yu, Jiang, Hui-Ling, Xiang, Yang, Zhou, Yong, Guan, Cha-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338586/
https://www.ncbi.nlm.nih.gov/pubmed/35907805
http://dx.doi.org/10.1186/s10020-022-00514-4