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Carboplatin dose calculations for patients with lung cancer: significant dose differences found depending on dosing equation choice

BACKGROUND: Carboplatin is the backbone cytotoxic agent for many chemotherapy regimens for lung cancer. Dosing of carboplatin is complicated due to its relationship to renal function and narrow therapeutic index. Overestimation of renal function may lead to supratherapeutic dosing and toxicity, whil...

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Detalles Bibliográficos
Autores principales: Akgül, Seçkin, Chan, Bryan A., Manders, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338596/
https://www.ncbi.nlm.nih.gov/pubmed/35906566
http://dx.doi.org/10.1186/s12885-022-09885-7