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Single cell gene expression profiling of nasal ciliated cells reveals distinctive biological processes related to epigenetic mechanisms in patients with severe COVID-19()

OBJECTIVE: To explore the molecular processes associated with cellular regulatory programs in patients with COVID-19, including gene activation or repression mediated by epigenetic mechanisms. We hypothesized that a comprehensive gene expression profiling of nasopharyngeal epithelial cells might exp...

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Detalles Bibliográficos
Autores principales: Diambra, Luis, Alonso, Andres M., Sookoian, Silvia, Pirola, Carlos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338837/
https://www.ncbi.nlm.nih.gov/pubmed/35926268
http://dx.doi.org/10.1016/j.compbiomed.2022.105895