Inhibition of c-MYC-miRNA 19 Pathway Sensitized CML K562 Cells to Etoposide via NHE1 Upregulation

As a previously discovered target of DNA damage, Na(+)/H(+) exchanger 1 (NHE1) plays a role in regulation of intracellular pH (pH(i)) through the extrusion of intracellular proton (H(+)) in exchange for extracellular sodium (Na(+)). Its abnormal expression and dysfunction have been reported in solid...

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Detalles Bibliográficos
Autores principales: Cao, Shannan, Xiong, Qingqing, Ding, Bowen, Wang, Xu, Wei, Feng, Sun, Qian, Yang, Fan, Luo, Jing, Chang, Guoqiang, Li, Suxin, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338868/
https://www.ncbi.nlm.nih.gov/pubmed/35915613
http://dx.doi.org/10.1155/2022/9306614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338868/
https://www.ncbi.nlm.nih.gov/pubmed/35915613
http://dx.doi.org/10.1155/2022/9306614

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