Cargando…

FTO mediated ERBB2 demethylation promotes tumor progression in esophageal squamous cell carcinoma cells

N(6)-methyladenosine (m(6)A) is the most prevalent and internal modification that occurs in the messenger RNAs of eukaryotes. However, knowledge of the impact of these modifications on gene expression regulation remains limited. By using the in vitro MeRIP-seq and RNA-seq assays, we discovered that...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Fangfang, Ge, Fangfang, Xie, Minghua, Li, Zhenyu, Zang, Chunbao, Kong, Lingsuo, Pu, Youguang, Zheng, Xucai, Tan, Yiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338917/
https://www.ncbi.nlm.nih.gov/pubmed/35524932
http://dx.doi.org/10.1007/s10585-022-10169-4