Sestrin2 remedies podocyte injury via orchestrating TSP-1/TGF-β1/Smad3 axis in diabetic kidney disease

Sestrin2 is identified as a stress-induced protein and could functionate in many aspects. In our study, we investigated the latent impact of Sestrin2 on podocyte injury and its molecular mechanism in vivo and in vitro in diabetic kidney disease (DKD). Sestrin2 was low-expressed in renal biopsies fro...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Shan, Shi, Chonglin, Bian, Yawei, Yang, Zhaohua, Mu, Lin, Wu, Haijiang, Duan, Huijun, Shi, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338940/
https://www.ncbi.nlm.nih.gov/pubmed/35908070
http://dx.doi.org/10.1038/s41419-022-05120-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338940/
https://www.ncbi.nlm.nih.gov/pubmed/35908070
http://dx.doi.org/10.1038/s41419-022-05120-0

Ejemplares similares