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c-di-AMP signaling plays important role in determining antibiotic tolerance phenotypes of Mycobacterium smegmatis

In this study, we probe the role of secondary messenger c-di-AMP in drug tolerance, which includes both persister and resistant mutant characterization of Mycobacterium smegmatis. Specifically, with the use of c-di-AMP null and overproducing mutants, we showed how c-di-AMP plays a significant role i...

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Detalles Bibliográficos
Autores principales: Pal, Aditya Kumar, Ghosh, Anirban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338955/
https://www.ncbi.nlm.nih.gov/pubmed/35907936
http://dx.doi.org/10.1038/s41598-022-17051-z