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Theaflavin 3-gallate inhibits the main protease (M(pro)) of SARS-CoV-2 and reduces its count in vitro

The main protease (M(pro)) of SARS-CoV-2 has been recognized as an attractive drug target because of its central role in viral replication. Our previous preliminary molecular docking studies showed that theaflavin 3-gallate (a natural bioactive molecule derived from theaflavin and found in high abun...

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Detalles Bibliográficos
Autores principales: Chauhan, Mahima, Bhardwaj, Vijay Kumar, Kumar, Asheesh, Kumar, Vinod, Kumar, Pawan, Enayathullah, M. Ghalib, Thomas, Jessie, George, Joel, Kumar, Bokara Kiran, Purohit, Rituraj, Kumar, Arun, Kumar, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338964/
https://www.ncbi.nlm.nih.gov/pubmed/35908093
http://dx.doi.org/10.1038/s41598-022-17558-5