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A maternal high-fat diet induces fetal origins of NASH-HCC in mice
Maternal overnutrition affects offspring susceptibility to nonalcoholic steatohepatitis (NASH). Male offspring from high-fat diet (HFD)-fed dams developed a severe form of NASH, leading to highly vascular tumor formation. The cancer/testis antigen HORMA domain containing protein 1 (HORMAD1), one of...
Autores principales: | Takiyama, Takao, Sera, Toshihiro, Nakamura, Masanori, Hoshino, Masato, Uesugi, Kentaro, Horike, Shin-ichi, Meguro-Horike, Makiko, Bessho, Ryoichi, Takiyama, Yuri, Kitsunai, Hiroya, Takeda, Yasutaka, Sawamoto, Kazuki, Yagi, Naoto, Nishikawa, Yuji, Takiyama, Yumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338981/ https://www.ncbi.nlm.nih.gov/pubmed/35907977 http://dx.doi.org/10.1038/s41598-022-17501-8 |
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