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Curcumin piperidone derivatives induce anti-proliferative and anti-migratory effects in LN-18 human glioblastoma cells

Curcumin has demonstrated potential cytotoxicity across various cell lines despite its poor bioavailability and rapid metabolism. Therefore, our group have synthesized curcuminoid analogues with piperidone derivatives, FLDP-5 and FLDP-8 to overcome these limitations. In this study, the analogues wer...

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Detalles Bibliográficos
Autores principales: Razali, Nur Syahirah Che, Lam, Kok Wai, Rajab, Nor Fadilah, A. Jamal, A. Rahman, Kamaluddin, Nurul Farahana, Chan, Kok Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338982/
https://www.ncbi.nlm.nih.gov/pubmed/35907913
http://dx.doi.org/10.1038/s41598-022-16274-4