Cholesterol sulfate alleviates ulcerative colitis by promoting cholesterol biosynthesis in colonic epithelial cells

Cholesterol sulfate, produced by hydroxysteroid sulfotransferase 2B1 (SULT2B1), is highly abundant in the intestine. Herein, we study the functional role and underlying intestinal epithelial repair mechanisms of cholesterol sulfate in ulcerative colitis. The levels of cholesterol and cholesterol sul...

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Detalles Bibliográficos
Autores principales: Xu, Dongke, Ma, Ruijun, Ju, Yi, Song, Xiaowei, Niu, Baolin, Hong, Wenting, Wang, Rong, Yang, Qin, Zhao, Zhi, Zhang, Yuchen, Zheng, Yufan, Bai, Qianming, Lv, Mingfang, Sun, Ning, Li, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338998/
https://www.ncbi.nlm.nih.gov/pubmed/35908039
http://dx.doi.org/10.1038/s41467-022-32158-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338998/
https://www.ncbi.nlm.nih.gov/pubmed/35908039
http://dx.doi.org/10.1038/s41467-022-32158-7

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