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Cholesterol sulfate alleviates ulcerative colitis by promoting cholesterol biosynthesis in colonic epithelial cells
Cholesterol sulfate, produced by hydroxysteroid sulfotransferase 2B1 (SULT2B1), is highly abundant in the intestine. Herein, we study the functional role and underlying intestinal epithelial repair mechanisms of cholesterol sulfate in ulcerative colitis. The levels of cholesterol and cholesterol sul...
Autores principales: | Xu, Dongke, Ma, Ruijun, Ju, Yi, Song, Xiaowei, Niu, Baolin, Hong, Wenting, Wang, Rong, Yang, Qin, Zhao, Zhi, Zhang, Yuchen, Zheng, Yufan, Bai, Qianming, Lv, Mingfang, Sun, Ning, Li, Xiaobo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338998/ https://www.ncbi.nlm.nih.gov/pubmed/35908039 http://dx.doi.org/10.1038/s41467-022-32158-7 |
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