Age-specific patterns of DBLα var diversity can explain why residents of high malaria transmission areas remain susceptible to Plasmodium falciparum blood stage infection throughout life

Immunity to Plasmodium falciparum is non-sterilising, thus individuals residing in malaria-endemic areas are at risk of infection throughout their lifetime. Here we seek to find a genomic epidemiological explanation for why residents of all ages harbour blood stage infections despite lifelong exposu...

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Detalles Bibliográficos
Autores principales: Ruybal-Pesántez, Shazia, Tiedje, Kathryn E., Pilosof, Shai, Tonkin-Hill, Gerry, He, Qixin, Rask, Thomas S., Amenga-Etego, Lucas, Oduro, Abraham R., Koram, Kwadwo A., Pascual, Mercedes, Day, Karen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339046/
https://www.ncbi.nlm.nih.gov/pubmed/35093396
http://dx.doi.org/10.1016/j.ijpara.2021.12.001