Toward in vivo proof of binding of (18)F-labeled inhibitor [(18)F]TRACK to peripheral tropomyosin receptor kinases

BACKGROUND: Tropomyosin receptor kinases (TrkA, TrkB, TrkC) are a family of tyrosine kinases primarily expressed in neuronal cells of the brain. Identification of oncogenic alterations in Trk expression as a driver in multiple tumor types has increased interest in their role in human cancers. Recent...

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Detalles Bibliográficos
Autores principales: Wuest, Melinda, Bailey, Justin J., Dufour, Jennifer, Glubrecht, Darryl, Omana, Vanessa, Johnston, Tom H., Brotchie, Jonathan M., Schirrmacher, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339071/
https://www.ncbi.nlm.nih.gov/pubmed/35907096
http://dx.doi.org/10.1186/s13550-022-00915-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339071/
https://www.ncbi.nlm.nih.gov/pubmed/35907096
http://dx.doi.org/10.1186/s13550-022-00915-w

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