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Comparative analysis of the testes from wild-type and Alkbh5-knockout mice using single-cell RNA sequencing

The RNA demethylase ALKBH5 is regarded as the “eraser” in N6-methyladenosine modification. ALKBH5 deficiency causes male infertility in mice; however, the mechanisms that confer disruption of spermatogenesis are not completely clear. In this study, we profiled testis samples from wild-type and Alkbh...

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Detalles Bibliográficos
Autores principales: Hong, Shihao, Shen, Xiaozhong, Luo, Chunhai, Sun, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339272/
https://www.ncbi.nlm.nih.gov/pubmed/35652742
http://dx.doi.org/10.1093/g3journal/jkac130