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Predicting which genes will respond to transcription factor perturbations

The ability to predict which genes will respond to the perturbation of a transcription factor serves as a benchmark for our systems-level understanding of transcriptional regulatory networks. In previous work, machine learning models have been trained to predict static gene expression levels in a bi...

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Detalles Bibliográficos
Autores principales: Kang, Yiming, Jung, Wooseok J, Brent, Michael R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339286/
https://www.ncbi.nlm.nih.gov/pubmed/35666184
http://dx.doi.org/10.1093/g3journal/jkac144