Conserved function of Drosophila Fancd2 monoubiquitination in response to double-strand DNA breaks

Fanconi anemia genes play key roles in metazoan DNA damage responses, and human FA mutations cause numerous disease phenotypes. In human cells, activating monoubiquitination of the Fanconi anemia protein Fancd2 occurs following diverse DNA damage stimuli. Monoubiquitinated Fancd2 forms nuclear foci...

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Detalles Bibliográficos
Autores principales: Clay, Delisa E, Jezuit, Erin A, Montague, Ruth A, Fox, Donald T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339327/
https://www.ncbi.nlm.nih.gov/pubmed/35595243
http://dx.doi.org/10.1093/g3journal/jkac129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339327/
https://www.ncbi.nlm.nih.gov/pubmed/35595243
http://dx.doi.org/10.1093/g3journal/jkac129

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