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High Glucose Aggravates Retinal Endothelial Cell Dysfunction by Activating the RhoA/ROCK1/pMLC/Connexin43 Signaling Pathway

PURPOSE: This research aims to explore the mechanism underlying the relationship between RhoA/ROCK signaling and Connexin43 (Cx43) in retinal endothelial cell dysfunction and to evaluate the protective effect of ROCK inhibitors against retinal endothelial cell dysfunction in diabetic retinopathy (DR...

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Detalles Bibliográficos
Autores principales: Zhao, Hongran, Kong, Hui, Wang, Wenjuan, Chen, Tianran, Zhang, Yuting, Zhu, Jing, Feng, Dandan, Cui, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339693/
https://www.ncbi.nlm.nih.gov/pubmed/35881407
http://dx.doi.org/10.1167/iovs.63.8.22