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Nanoscale Porphyrin Metal-Organic Frameworks Deliver siRNA for Alleviating Early Pulmonary Fibrosis in Acute Lung Injury

Acute lung injury (ALI) has high mortality and still lacks novel and efficient therapies. Zinc finger E-box binding homeobox 1 and 2 (ZEB1/2) are highly expressed in the early stage of ALI and are positively correlated with the progression of pulmonary fibrosis. Herein, we developed a nanoscale Zr(I...

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Detalles Bibliográficos
Autores principales: Weng, Changmei, Li, Guanhua, Zhang, Dongdong, Duan, Zhaoxia, Chen, Kuijun, Zhang, Jieyuan, Li, Tao, Wang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339993/
https://www.ncbi.nlm.nih.gov/pubmed/35923570
http://dx.doi.org/10.3389/fbioe.2022.939312