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Role of post-translational modifications on the alpha-synuclein aggregation-related pathogenesis of Parkinson’s disease

Together with neuronal loss, the existence of insoluble inclusions of alpha-synuclein (α-syn) in the brain is widely accepted as a hallmark of synucleinopathies including Parkinson’s disease (PD), multiple system atrophy, and dementia with Lewy body. Because the α-syn aggregates are deeply involved...

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Detalles Bibliográficos
Autores principales: Yoo, Hajung, Lee, Jeongmin, Kim, Bokwang, Moon, Heechang, Jeong, Huisu, Lee, Kyungmi, Song, Woo Jeung, Hur, Junho K., Oh, Yohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340086/
https://www.ncbi.nlm.nih.gov/pubmed/35733294
http://dx.doi.org/10.5483/BMBRep.2022.55.7.073