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Alternative splicing variant of NRP/B promotes tumorigenesis of gastric cancer

Gastrointestinal cancer is associated with a high mortality rate. Here, we report that the splice variant of NRP/B contributes to tumorigenic activity in highly malignant gastric cancer through dissociation from the tumor repressor, HDAC5. NRP/B mRNA expression is significantly higher in the human g...

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Detalles Bibliográficos
Autores principales: Kim, Aram, Mok, Bo Ram, Hahn, Soojung, Yoo, Jongman, Kim, Dong Hyun, Kim, Tae-Aug
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340087/
https://www.ncbi.nlm.nih.gov/pubmed/35725010
http://dx.doi.org/10.5483/BMBRep.2022.55.7.034