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Inhibition of mitoNEET induces Pink1-Parkin-mediated mitophagy

MitoNEET, a mitochondrial outer membrane protein containing the Asn-Glu-Glu-Thr (NEET) sequence, controls the formation of intermitochondrial junctions and confers autophagy resistance. Moreover, mitoNEET as a mitochondrial substrate undergoes ubiquitination by activated Parkin during the initiation...

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Detalles Bibliográficos
Autores principales: Lee, Seunghee, Lee, Sangguk, Lee, Seon-Jin, Chung, Su Wol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340089/
https://www.ncbi.nlm.nih.gov/pubmed/35725011
http://dx.doi.org/10.5483/BMBRep.2022.55.7.040