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Systematic Investigation of LC Miniaturization to Increase Sensitivity in Wide-Target LC-MS-Based Trace Bioanalysis of Small Molecules

Covering a wide spectrum of molecules is essential for global metabolome assessment. While metabolomics assays are most frequently carried out in microbore LC-MS analysis, reducing the size of the analytical platform has proven its ability to boost sensitivity for specific -omics applications. In th...

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Detalles Bibliográficos
Autores principales: Fitz, Veronika, El Abiead, Yasin, Berger, Daniel, Koellensperger, Gunda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340153/
https://www.ncbi.nlm.nih.gov/pubmed/35923463
http://dx.doi.org/10.3389/fmolb.2022.857505