SIRT3 inhibitor 3-TYP exacerbates thioacetamide-induced hepatic injury in mice

The purpose of the study was to explore the effects of SIRT3 inhibitor 3-TYP on acute liver failure (ALF) in mice and its underlying mechanism. The mice were treated with thioacetamide (TAA, 300 mg/kg) for inducing ALF model. 3-TYP (50 mg/kg) was administered 2 h prior to TAA. The liver histological...

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Detalles Bibliográficos
Autores principales: Shi, Chunxia, Jiao, Fangzhou, Wang, Yao, Chen, Qian, Wang, Luwen, Gong, Zuojiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340259/
https://www.ncbi.nlm.nih.gov/pubmed/35923224
http://dx.doi.org/10.3389/fphys.2022.915193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340259/
https://www.ncbi.nlm.nih.gov/pubmed/35923224
http://dx.doi.org/10.3389/fphys.2022.915193

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