Pharmacological Inhibition of STING/TBK1 Signaling Attenuates Myeloid Fibroblast Activation and Macrophage to Myofibroblast Transition in Renal Fibrosis

Renal fibrosis is an important pathological biomarker of chronic kidney disease (CKD). Stimulator of interferon genes/TANK binding kinase 1 (STING/TBK1) axis has been identified as the main regulator of innate immune response and closely related to fibrotic disorder. However, the role of STING/TBK1...

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Detalles Bibliográficos
Autores principales: Zeng, Haimei, Gao, Ying, Yu, Wenqiang, Liu, Jiping, Zhong, Chaoqun, Su, Xi, Wen, Shihong, Liang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340478/
https://www.ncbi.nlm.nih.gov/pubmed/35924048
http://dx.doi.org/10.3389/fphar.2022.940716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340478/
https://www.ncbi.nlm.nih.gov/pubmed/35924048
http://dx.doi.org/10.3389/fphar.2022.940716

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