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Pharmacological Inhibition of STING/TBK1 Signaling Attenuates Myeloid Fibroblast Activation and Macrophage to Myofibroblast Transition in Renal Fibrosis
Renal fibrosis is an important pathological biomarker of chronic kidney disease (CKD). Stimulator of interferon genes/TANK binding kinase 1 (STING/TBK1) axis has been identified as the main regulator of innate immune response and closely related to fibrotic disorder. However, the role of STING/TBK1...
Autores principales: | Zeng, Haimei, Gao, Ying, Yu, Wenqiang, Liu, Jiping, Zhong, Chaoqun, Su, Xi, Wen, Shihong, Liang, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340478/ https://www.ncbi.nlm.nih.gov/pubmed/35924048 http://dx.doi.org/10.3389/fphar.2022.940716 |
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