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Heterogeneity of Organization of Subcompartments in DSB Repair Foci

Cells assemble compartments around DNA double-strand breaks (DSBs). The assembly of this compartment is dependent on the phosphorylation of histone H2AX, the binding of MDC1 to phosphorylated H2AX, and the assembly of downstream signaling and repair components. The decision on whether to use homolog...

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Detalles Bibliográficos
Autores principales: Abate, Natnael G., Hendzel, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340495/
https://www.ncbi.nlm.nih.gov/pubmed/35923694
http://dx.doi.org/10.3389/fgene.2022.887088