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SAA fibrils involved in AA amyloidosis are similar in bulk and by single particle reconstitution: A MAS solid-state NMR study

AA amyloidosis is one of the most prevalent forms of systemic amyloidosis and affects both humans and other vertebrates. In this study, we compare MAS solid-state NMR data with a recent cryo-EM study of fibrils involving full-length murine SAA1.1. We address the question whether the specific require...

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Detalles Bibliográficos
Autores principales: Sundaria, Arpita, Liberta, Falk, Savran, Dilan, Sarkar, Riddhiman, Rodina, Natalia, Peters, Carsten, Schwierz, Nadine, Haupt, Christian, Schmidt, Matthias, Reif, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340516/
https://www.ncbi.nlm.nih.gov/pubmed/35924280
http://dx.doi.org/10.1016/j.yjsbx.2022.100069