Cargando…
Development of a fully human anti‐GITR antibody with potent antitumor activity using H2L2 mice
Glucocorticoid‐induced TNF receptor‐related (GITR) can act as a co‐stimulatory receptor, representing a potential target for safely enhancing immunotherapy efficacy. GITR is triggered by a GITR ligand or an agonist antibody and activates CD8(+) and CD4(+) effector T cells, reducing tumor‐infiltratin...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340783/ https://www.ncbi.nlm.nih.gov/pubmed/35674216 http://dx.doi.org/10.1002/2211-5463.13451 |