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Ulinastatin promotes macrophage efferocytosis and ameliorates lung inflammation via the ERK5/Mer signaling pathway

Acute lung injury (ALI) is a pneumonic response characterized by neutrophil infiltration. Macrophage efferocytosis is the process whereby macrophages remove apoptotic cells, and is required for ALI inflammation to subside. The glycoprotein ulinastatin (UTI) has an anti‐inflammatory effect during the...

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Detalles Bibliográficos
Autores principales: Li, Jinju, Shao, Rongge, Xie, Qiuwen, Qin, Ke, Ming, ShaoPeng, Xie, Yongguo, Du, XueKe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340873/
https://www.ncbi.nlm.nih.gov/pubmed/35778889
http://dx.doi.org/10.1002/2211-5463.13461