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Structural insights into the binding of SARS-CoV-2, SARS-CoV, and hCoV-NL63 spike receptor-binding domain to horse ACE2

Severe acute respiratory syndrome coronavirus (SARS-CoV), SARS-CoV-2, and human coronavirus (hCoV)-NL63 utilize ACE2 as the functional receptor for cell entry, which leads to zoonotic infection. Horses (Equus caballus) attracted our attention because the spike protein receptor-binding domains (RBDs)...

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Detalles Bibliográficos
Autores principales: Lan, Jun, Chen, Peng, Liu, Weiming, Ren, Wenlin, Zhang, Linqi, Ding, Qiang, Zhang, Qi, Wang, Xinquan, Ge, Jiwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341007/
https://www.ncbi.nlm.nih.gov/pubmed/35917815
http://dx.doi.org/10.1016/j.str.2022.07.005