Design, synthesis, and molecular docking studies of diphenylquinoxaline-6-carbohydrazide hybrids as potent α-glucosidase inhibitors

A novel series of diphenylquinoxaline-6-carbohydrazide hybrids 7a–o were rationally designed and synthesized as anti-diabetic agents. All synthesized compounds 7a–o were screened as possible α-glucosidase inhibitors and exhibited good inhibitory activity with IC(50) values in the range of 110.6 ± 6....

Descripción completa

Detalles Bibliográficos
Autores principales: Pedrood, Keyvan, Rezaei, Zahra, Khavaninzadeh, Kimia, Larijani, Bagher, Iraji, Aida, Hosseini, Samanesadat, Mojtabavi, Somayeh, Dianatpour, Mehdi, Rastegar, Hossein, Faramarzi, Mohammad Ali, Hamedifar, Haleh, Hajimiri, Mir Hamed, Mahdavi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341091/
https://www.ncbi.nlm.nih.gov/pubmed/35909126
http://dx.doi.org/10.1186/s13065-022-00848-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341091/
https://www.ncbi.nlm.nih.gov/pubmed/35909126
http://dx.doi.org/10.1186/s13065-022-00848-4

Ejemplares similares