Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry

BACKGROUND: Oncolytic viruses are considered part of immunotherapy and have shown promise in preclinical experiments and clinical trials. Results from these studies have suggested that tumor microenvironment remodeling is required to achieve an effective response in solid tumors. Here, we assess the...

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Detalles Bibliográficos
Autores principales: Nguyen, Teresa T, Shin, Dong Ho, Sohoni, Sagar, Singh, Sanjay K, Rivera-Molina, Yisel, Jiang, Hong, Fan, Xuejun, Gumin, Joy, Lang, Frederick F, Alvarez-Breckenridge, Christopher, Godoy-Vitorino, Filipa, Zhu, Lisha, Zheng, W Jim, Zhai, Lijie, Ladomersky, Erik, Lauing, Kristen L, Alonso, Marta M, Wainwright, Derek A, Gomez-Manzano, Candelaria, Fueyo, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341188/
https://www.ncbi.nlm.nih.gov/pubmed/35902132
http://dx.doi.org/10.1136/jitc-2022-004935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341188/
https://www.ncbi.nlm.nih.gov/pubmed/35902132
http://dx.doi.org/10.1136/jitc-2022-004935

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