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Performance of Cardiotropic rAAV Vectors Is Dependent on Production Method

Gene therapy is making significant impact on a modest, yet growing, number of human diseases. Justifiably, the preferred viral vector for clinical use is that based on recombinant adeno-associated virus (rAAV). There is a need to scale up rAAV vector production with the transition from pre-clinical...

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Detalles Bibliográficos
Autores principales: Rao, Renuka, Farraha, Melad, Logan, Grant J., Igoor, Sindhu, Kok, Cindy Y., Chong, James J. H., Alexander, Ian E., Kizana, Eddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341392/
https://www.ncbi.nlm.nih.gov/pubmed/35893689
http://dx.doi.org/10.3390/v14081623