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Abnormal TP53 Predicts Risk of Progression in Patients With Barrett’s Esophagus Regardless of a Diagnosis of Dysplasia

BACKGROUND AND AIMS: Barrett’s esophagus (BE) is the precursor to esophageal adenocarcinoma. A major challenge is identifying the small group with BE who will progress to advanced disease from the many who will not. Assessment of p53 status has promise as a predictive biomarker, but analytic limitat...

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Detalles Bibliográficos
Autores principales: Redston, Mark, Noffsinger, Amy, Kim, Anthony, Akarca, Fahire G., Rara, Marianne, Stapleton, Diane, Nowden, Laurel, Lash, Richard, Bass, Adam J., Stachler, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341495/
https://www.ncbi.nlm.nih.gov/pubmed/34757142
http://dx.doi.org/10.1053/j.gastro.2021.10.038