Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers

Chromosomal translocations are important drivers of haematological malignancies whereby proto-oncogenes are activated by juxtaposition with enhancers, often called enhancer hijacking. We analyzed the epigenomic consequences of rearrangements between the super-enhancers of the immunoglobulin heavy lo...

Descripción completa

Detalles Bibliográficos
Autores principales: Mikulasova, Aneta, Kent, Daniel, Trevisan-Herraz, Marco, Karataraki, Nefeli, Fung, Kent T.M., Ashby, Cody, Cieslak, Agata, Yaccoby, Shmuel, van Rhee, Frits, Zangari, Maurizio, Thanendrarajan, Sharmilan, Schinke, Carolina, Morgan, Gareth J., Asnafi, Vahid, Spicuglia, Salvatore, Brackley, Chris A., Corcoran, Anne E., Hambleton, Sophie, Walker, Brian A., Rico, Daniel, Russell, Lisa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341503/
https://www.ncbi.nlm.nih.gov/pubmed/34933939
http://dx.doi.org/10.1101/gr.276042.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341503/
https://www.ncbi.nlm.nih.gov/pubmed/34933939
http://dx.doi.org/10.1101/gr.276042.121

Ejemplares similares