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Somatic retrotransposition in the developing rhesus macaque brain

The retrotransposon LINE-1 (L1) is central to the recent evolutionary history of the human genome and continues to drive genetic diversity and germline pathogenesis. However, the spatiotemporal extent and biological significance of somatic L1 activity are poorly defined and are virtually unexplored...

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Detalles Bibliográficos
Autores principales: Billon, Victor, Sanchez-Luque, Francisco J., Rasmussen, Jay, Bodea, Gabriela O., Gerhardt, Daniel J., Gerdes, Patricia, Cheetham, Seth W., Schauer, Stephanie N., Ajjikuttira, Prabha, Meyer, Thomas J., Layman, Cora E., Nevonen, Kimberly A., Jansz, Natasha, Garcia-Perez, Jose L., Richardson, Sandra R., Ewing, Adam D., Carbone, Lucia, Faulkner, Geoffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341517/
https://www.ncbi.nlm.nih.gov/pubmed/35728967
http://dx.doi.org/10.1101/gr.276451.121