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IL-17A deletion reduces sevoflurane-induced neurocognitive impairment in neonatal mice by inhibiting NF-κB signaling pathway

We investigated the role of IL-17A in sevoflurane-inducedneurocognitive impairment in neonatal mice. Seventy-two wild-type (WT) and 42 IL-17A knockout (KO) neonatal mice were randomly divided into WT (n = 36), IL-17A(−/−) (n = 6), sevoflurane (Sev, n = 36), and IL-17A(−/−) + sevoflurane (IL-17A(−/−)...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Li, Yanan, Yin, Chunping, Gao, Mingyang, Yu, Jiaxu, Guo, Junfei, Xian, Xiaohui, Hou, Zhiyong, Wang, Qiujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342424/
https://www.ncbi.nlm.nih.gov/pubmed/35758051
http://dx.doi.org/10.1080/21655979.2022.2090608