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An autologous colonic organoid‐derived monolayer model to study immune: bacterial interactions in Crohn's disease patients

OBJECTIVES: Crohn's disease (CD) initiation and pathogenesis are believed to involve an environmental trigger in a genetically susceptible person that results in an immune response against commensal gut bacteria, leading to a compromised intestinal epithelial barrier and a cycle of inflammation...

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Detalles Bibliográficos
Autores principales: Angus, Hamish CK, Urbano, Paulo CM, Laws, Gemma A, Fan, Shijun, Gadeock, Safina, Schultz, Michael, Butt, Grant, Highton, Andrew J, Kemp, Roslyn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342672/
https://www.ncbi.nlm.nih.gov/pubmed/35924188
http://dx.doi.org/10.1002/cti2.1407