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An autologous colonic organoid‐derived monolayer model to study immune: bacterial interactions in Crohn's disease patients
OBJECTIVES: Crohn's disease (CD) initiation and pathogenesis are believed to involve an environmental trigger in a genetically susceptible person that results in an immune response against commensal gut bacteria, leading to a compromised intestinal epithelial barrier and a cycle of inflammation...
Autores principales: | Angus, Hamish CK, Urbano, Paulo CM, Laws, Gemma A, Fan, Shijun, Gadeock, Safina, Schultz, Michael, Butt, Grant, Highton, Andrew J, Kemp, Roslyn A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342672/ https://www.ncbi.nlm.nih.gov/pubmed/35924188 http://dx.doi.org/10.1002/cti2.1407 |
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