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To what extent naringenin binding and membrane depolarization shape mitoBK channel gating—A machine learning approach
The large conductance voltage- and Ca(2+)-activated K(+) channels from the inner mitochondrial membrane (mitoBK) are modulated by a number of factors. Among them flavanones, including naringenin (Nar), arise as a promising group of mitoBK channel regulators from a pharmacological point of view. It i...
Autores principales: | Richter-Laskowska, Monika, Trybek, Paulina, Bednarczyk, Piotr, Wawrzkiewicz-Jałowiecka, Agata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342765/ https://www.ncbi.nlm.nih.gov/pubmed/35857767 http://dx.doi.org/10.1371/journal.pcbi.1010315 |
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