Chemical evidence for the tradeoff-in-the-nephron hypothesis to explain secondary hyperparathyroidism

BACKGROUND: Secondary hyperparathyroidism (SHPT) complicates advanced chronic kidney disease (CKD) and causes skeletal and other morbidity. In animal models of CKD, SHPT was prevented and reversed by reduction of dietary phosphate in proportion to GFR, but the phenomena underlying these observations...

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Detalles Bibliográficos
Autores principales: Phelps, Kenneth R., Gemoets, Darren E., May, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342777/
https://www.ncbi.nlm.nih.gov/pubmed/35913960
http://dx.doi.org/10.1371/journal.pone.0272380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342777/
https://www.ncbi.nlm.nih.gov/pubmed/35913960
http://dx.doi.org/10.1371/journal.pone.0272380

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