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PEGylated SLN as a Promising Approach for Lymphatic Delivery of Gefitinib to Lung Cancer

PURPOSE: The present study aimed to develop gefitinib-loaded solid lipid nanoparticles (GEF-SLN), and GEF-loaded PEGylated SLN (GEF-P-SLN) for targeting metastatic lung cancer through the lymphatic system. METHODS: The prepared SLNs were characterized in terms of physicochemical properties, entrapme...

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Detalles Bibliográficos
Autores principales: Sherif, Abdelrahman Y, Harisa, Gamaleldin I, Alanazi, Fars K, Nasr, Fahd A, Alqahtani, Ali S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342893/
https://www.ncbi.nlm.nih.gov/pubmed/35924261
http://dx.doi.org/10.2147/IJN.S365974