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On-bead DNA synthesis triggered by allosteric probe for detection of carcinoembryonic antigen

Sensitive quantification of protein biomarkers is highly desired for clinical diagnosis and treatment. Yet, unlike DNA/RNA which can be greatly amplified by PCR/RT-PCR, the amplification and detection of trace amount of proteins remain a great challenge. Here, we combined allosteric probe (AP) with...

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Detalles Bibliográficos
Autores principales: Ling, Min, Luo, Na, Cui, Lanyu, Cao, Yongqiang, Ning, Xueping, Sun, Jian, Xu, Xiaoping, He, Shengbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342938/
https://www.ncbi.nlm.nih.gov/pubmed/35915288
http://dx.doi.org/10.1007/s00604-022-05404-4