Therapeutic deep brain stimulation disrupts movement-related subthalamic nucleus activity in parkinsonian mice

Subthalamic nucleus deep brain stimulation (STN DBS) relieves many motor symptoms of Parkinson’s disease (PD), but its underlying therapeutic mechanisms remain unclear. Since its advent, three major theories have been proposed: (1) DBS inhibits the STN and basal ganglia output; (2) DBS antidromicall...

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Detalles Bibliográficos
Autores principales: Schor, Jonathan S, Gonzalez Montalvo, Isabelle, Spratt, Perry WE, Brakaj, Rea J, Stansil, Jasmine A, Twedell, Emily L, Bender, Kevin J, Nelson, Alexandra B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342952/
https://www.ncbi.nlm.nih.gov/pubmed/35786442
http://dx.doi.org/10.7554/eLife.75253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342952/
https://www.ncbi.nlm.nih.gov/pubmed/35786442
http://dx.doi.org/10.7554/eLife.75253

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