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Frequency-specific medial septal nucleus deep brain stimulation improves spatial memory in MK-801-treated male rats

BACKGROUND: Few treatments exist for the cognitive symptoms of schizophrenia. Pharmacological agents resulting in glutamate N-methyl-d-aspartate (NMDA) receptor hypofunction, such as MK-801, mimic many of these symptoms and disrupt neural activity. Recent evidence suggests that deep brain stimulatio...

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Detalles Bibliográficos
Autores principales: Zepeda, Nancy C., Crown, Lindsey M., Medvidovic, Sasha, Choi, Wooseong, Sheth, Megha, Bergosh, Matthew, Gifford, Raymond, Folz, Caroline, Lam, Phillip, Lu, Gengxi, Featherstone, Robert, Liu, Charles Y., Siegel, Steven J., Lee, Darrin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343054/
https://www.ncbi.nlm.nih.gov/pubmed/35584727
http://dx.doi.org/10.1016/j.nbd.2022.105756